| Primary Identifier | MGI:3527998 | Allele Type | Transgenic |
| Attribute String | Humanized sequence, Inserted expressed sequence | Gene | Tg(SFTPC-TP53*R273H)1Mavc |
| Strain of Origin | FVB/N | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | A 1.8 kb fragment containing a mutant human TP53 with an arginine to histidine mutation at codon 273 was cloned into the EcoRI site of the rabbit Beta-globin exon 3 and placed under the transcriptional control of the human Surfactant associated protein C (SFTPC) promoter. ~7 copies of the transgene were incorporated into the genome. |
