Primary Identifier | IPR026165 | Type | Family |
Short Name | CKAP2_fam |
description | Mouse CKAP2 has been shown to possess microtubule stabilising properties []and is involved in regulating aneuploidy, cell cycle, and cell death in a p53-dependent manner []. In human, CKAMP2 is up-regulated in primary gastric cancers []. It has been shown that human CKAP2 is degraded by APC/C-Cdh1 during mitotic exit and that a tight regulation of CKAP2 protein level is important for mitotic progression []. |