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Protein Domain : Cytoskeleton-associated protein 2 family

Primary Identifier  IPR026165 Type  Family
Short Name  CKAP2_fam
description  Mouse CKAP2 has been shown to possess microtubule stabilising properties []and is involved in regulating aneuploidy, cell cycle, and cell death in a p53-dependent manner []. In human, CKAMP2 is up-regulated in primary gastric cancers []. It has been shown that human CKAP2 is degraded by APC/C-Cdh1 during mitotic exit and that a tight regulation of CKAP2 protein level is important for mitotic progression [].

0 Child Features

0 Parent Features

1 Protein Domain Regions