Primary Identifier | MGI:2182329 | Allele Type | Targeted |
Attribute String | Null/knockout, Reporter | Gene | Dbx1 |
Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
Is Recombinase | false | Is Wild Type | false |
molecularNote | The entire coding region (exons 1 through 4) was replaced by a cassette comprised of an nls-lacZ gene and a floxed neo gene. Endogenous transcript and protein were were absent from the spinal cords of homozygous mice. The expression pattern of beta-galactosidse was found to resemble that of the endogenous gene in neural progenitor cells. |