Primary Identifier | MGI:6149963 | Allele Type | Endonuclease-mediated |
Attribute String | Not Specified | Gene | Ptpn22 |
Strain of Origin | NOD/ShiLtJ | Is Recombinase | false |
Is Wild Type | false |
molecularNote | CRISPR-targeting generated a 4 nucleotide substitution in exon 14 that results in the amino acid substitution of tryptophan for arginine at position 619 (R619W). An additional silent mutation (CTC to CTT) was introduced at amino acid position 616. |