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Allele : Tg(CD19-BTK*Y223F)AM02Rwhe transgene insertion AM02, Rudolf Hendriks

Primary Identifier  MGI:3709258 Allele Type  Transgenic
Attribute String  Inserted expressed sequence Gene  Tg(CD19-BTK*Y223F)AM02Rwhe
Strain of Origin  FVB Is Recombinase  false
Is Wild Type  false
molecularNote  A composite fragment composed of 400bp from exons 1-3 of a BTK cDNA as well as 27kb genomic fragment containing exons 3-19 of BTK was placed under the control of the promoter region of human CD19. A Y223F mutation was introduced into this construct by double stranded site-directed mutagenesis.
  • mutations:
  • Insertion
  • synonyms:
  • CD19-hBtk<Y223F>,
  • CD19-hBtk<Y223F>
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1 Feature

Trail: Allele

Genome

1 Expresses

Trail: Allele

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories

Trail: Allele