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Comment :

Type  MGI:General Description  in a model of acute dextran sodium sulfate (DSS)-induced colitis, homozygotes display increased susceptibility to a low-dose (2.5%) of DSS that causes mild colonic epithelial injury in wild-type mice notably, homozygotes treated with low-dose DSS display intermediate damage of the colonic mucosa relative to wild-type and Ptgs2tm1Unc homozygous mutant mice