Primary Identifier | IPR019440 | Type | Family |
Short Name | MAU2 |
description | This entry represents the chromatid cohesion factor Mau2 and its homologues, including Scc4 from budding yeasts and Ssl3 from fission yeasts. Scc4 is a subunit of the cohesin loading factor complex (Scc2-Scc4), which is required for the loading of cohesin complexes onto chromosomes []. Ssl3 is in complex with Mis4 (Scc2 homologue) and is required in G1 for cohesin binding to chromosomes []. Animal Mau2 interacts with Nipbl (Scc2 orthologue), and both proteins are involved in sister chromatid cohesion and segregation [, , ]. |