|  Help  |  About  |  Contact Us

Protein Coding Gene : Epgn epithelial mitogen

Primary Identifier  MGI:1919170 Organism  mouse, laboratory
Chromosome  5 NCBI Gene Number  71920
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables epidermal growth factor receptor binding activity; growth factor activity; and transmembrane receptor protein tyrosine kinase activator activity. Involved in epidermal growth factor receptor signaling pathway; positive regulation of epithelial cell proliferation; and positive regulation of mitotic nuclear division. Acts upstream of or within MAPK cascade. Is active in extracellular space. Is expressed in several structures, including alimentary system; arterial system; dorsal root ganglion; hair follicle; and male reproductive gland or organ. Orthologous to human EPGN (epithelial mitogen).
PHENOTYPE: Mice homozygous for a knock-out allele exhibit moderate increase in absolute pancreas and spleen weight but normal epidermis and pilosebaceous unit development. [provided by MGI curators]
  • synonyms:
  • epithelial mitogen,
  • Epgn,
  • epigen,
  • RIKEN cDNA 2310069M11 gene,
  • 2310069M11Rik

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

4 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

22 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For