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Protein Domain : E3 ubiquitin-protein ligase HECTD3

Primary Identifier  IPR042469 Type  Family
Short Name  HECTD3
description  E3 ubiquitin-protein ligase HECTD3 is an E3 ubiquitin ligase that regulates ubiquitination and degradation of Tara [], MASTL and LKB1 []. HECTD3 interacts with HSP90 and is involved in the HSP90-dependent degradation of CRAF protein []. It has been shown to interact and stabilize MALT1 (mucosa-associated lymphoid tissue 1), and may hence promote cell survival [].

0 Child Features

0 Parent Features

2 Protein Domain Regions