First Author | Sorimachi H | Year | 1996 |
Journal | Biochim Biophys Acta | Volume | 1309 |
Issue | 1-2 | Pages | 37-41 |
PubMed ID | 8950173 | Mgi Jnum | J:36790 |
Mgi Id | MGI:84212 | Doi | 10.1016/s0167-4781(96)00135-2 |
Citation | Sorimachi H, et al. (1996) Primary sequences of rat mu-calpain large and small subunits are, respectively, moderately and highly similar to those of human. Biochim Biophys Acta 1309(1-2):37-41 |
abstractText | cDNAs for rat mu-calpain large subunit and the calpain small subunit were cloned and sequenced. The large subunit encodes 713 amino-acid residues, which includes one deletion compared to that of human. The overall similarity is 89% to human mu-type, which is slightly lower than those compared between other types of calpain large subunits of rat and human (93-94%). On the other hand, the small subunit showed high conservation, being 94.0% identical to that of human. With these sequences, primary structures of all rat calpain subunits that have been considered to exist were completely elucidated. |