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Publication : Primary sequences of rat mu-calpain large and small subunits are, respectively, moderately and highly similar to those of human.

First Author  Sorimachi H Year  1996
Journal  Biochim Biophys Acta Volume  1309
Issue  1-2 Pages  37-41
PubMed ID  8950173 Mgi Jnum  J:36790
Mgi Id  MGI:84212 Doi  10.1016/s0167-4781(96)00135-2
Citation  Sorimachi H, et al. (1996) Primary sequences of rat mu-calpain large and small subunits are, respectively, moderately and highly similar to those of human. Biochim Biophys Acta 1309(1-2):37-41
abstractText  cDNAs for rat mu-calpain large subunit and the calpain small subunit were cloned and sequenced. The large subunit encodes 713 amino-acid residues, which includes one deletion compared to that of human. The overall similarity is 89% to human mu-type, which is slightly lower than those compared between other types of calpain large subunits of rat and human (93-94%). On the other hand, the small subunit showed high conservation, being 94.0% identical to that of human. With these sequences, primary structures of all rat calpain subunits that have been considered to exist were completely elucidated.
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