| Primary Identifier | MGI:5548172 | Allele Type | Targeted |
| Attribute String | Hypomorph, Modified isoform(s) | Gene | Pdgfa |
| Transmission | Germline | Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A neomycin resistance cassette inserted into intron 5, deleting the 5' splice site upstream of exon 6. This allele is predicted to produce only the short form transcript but not express the long form. Q-PCR confirmed reduced total transcript expression in the lung and skin, but not other tissues. Authors state that this allele might be hypomorphic in the lungs but not other tissues. |
