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Protein Coding Gene : Supt16 SPT16, facilitates chromatin remodeling subunit
Primary Identifier  MGI:1890948 Organism  mouse, laboratory
Chromosome  14 NCBI Gene Number  114741
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable nucleosome binding activity. Predicted to be involved in nucleosome disassembly and transcription elongation by RNA polymerase II. Predicted to act upstream of or within DNA repair and DNA replication. Predicted to be located in nucleoplasm. Predicted to be part of FACT complex. Is expressed in several structures, including alimentary system; brain; hindlimb phalanx; integumental system; and sensory organ. Human ortholog(s) of this gene implicated in neurodevelopmental disorder with dysmorphic facies and thin corpus callosum. Orthologous to human SUPT16H (SPT16 homolog, facilitates chromatin remodeling subunit).
  • synonyms:
  • Fact140,
  • Supt16h,
  • Supt16,
  • SPT16, facilitates chromatin remodeling subunit,
  • Spt16,
  • Cdc68,
  • suppressor of Ty 16 homolog (S. cerevisiae)
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Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

1 Involved In Mutations

Trail: ProteinCodingGene

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

10 Pathways

Trail: ProteinCodingGene

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

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