| First Author | Laval SH | Year | 1993 |
| Journal | Genomics | Volume | 15 |
| Issue | 3 | Pages | 483-91 |
| PubMed ID | 8468042 | Mgi Jnum | J:4249 |
| Mgi Id | MGI:52745 | Doi | 10.1006/geno.1993.1098 |
| Citation | Laval SH, et al. (1993) Novel sequences conserved on the human and mouse X chromosomes. Genomics 15(3):483-91 |
| abstractText | We have cloned and mapped 28 single-copy probes from a pool of cosmids derived from the human X chromosome. Four of the probes detected strongly conserved sequences in murine DNA; all have been localized to the proximal region of the human X chromosome short arm. Comparative mapping of these sequences in the mouse genome demonstrates that, while X linkage is conserved, this region of the human X chromosome is not maintained as a contiguous segment on the mouse X chromosome. The mapping of one novel conserved sequence between Plp and Pdha1 on the mouse X chromosome defines a previously unknown region of homology. The mapping of another probe that detects a novel sequence family (DXF34) close to the X chromosome centromere in both species suggests that a block of pericentromeric material is conserved between the X chromosomes of man and mouse. |
