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Allele : Tg(tetO-Mtor*)#Atai transgene insertion, Atsu Aiba

Primary Identifier  MGI:5634714 Allele Type  Transgenic
Attribute String  Constitutively active, Inserted expressed sequence Gene  Tg(tetO-Mtor*)#Atai
Strain of Origin  C57BL/6 Is Recombinase  false
Is Wild Type  false
molecularNote  This transgene consists of the tetracycline-responsive element and the mutant rat Mtor kinase, which harbors four point mutations in the FKBP12-rapamycin binding and kinase domains (V2198A, L2216H, L2260P, and I2017T) with a FLAG tag at the N terminus. Expression of active Mtor depends on binding of tTA to the tetO promoter. The pound symbol (#) is used when line is not specified and/or lines are pooled.
  • mutations:
  • Insertion
  • synonyms:
  • TRE-mTOR<SL1+IT>,
  • TRE-mTOR<SL1+IT>
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1 Feature

Trail: Allele

Genome

1 Expresses

Trail: Allele

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories

Trail: Allele