| First Author | Thifault S | Year | 2002 |
| Journal | Brain Res Bull | Volume | 58 |
| Issue | 2 | Pages | 213-8 |
| PubMed ID | 12127020 | Mgi Jnum | J:79005 |
| Mgi Id | MGI:2386814 | Doi | 10.1016/s0361-9230(02)00782-7 |
| Citation | Thifault S, et al. (2002) Comparisons between C57BL/6J and A/J mice in motor activity and coordination, hole-poking, and spatial learning. Brain Res Bull 58(2):213-8 |
| abstractText | The C57BL/6J (B6) inbred mouse strain was compared to the A/J inbred strain for motor activity in an open-field, exploration of a hole-board, motor coordination in the coat-hanger test, and spatial learning in the Morris water maze. B6 mice displayed a higher number of segment crossings in the open-field and of hole-poking responses than A/J mice. The performance of B6 mice was superior to that of A/J mice not only in the submerged but also in the visible platform version of the Morris water maze. By contrast to their hypoactivity, the A/J strain had shorter movement times in the coat-hanger test, indicating faster motor speed, although the groups did not differ in latencies before falling. These results indicate that recombinant inbred or congenic strains derived from B6 and A/J mice offer considerable potential for discerning the genetic basis of several behavioral phenotypes. |
