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Allele : Pou4f2<tm1.1Xmu> POU domain, class 4, transcription factor 2; targeted mutation 1.1, Xiuqian Mu

Primary Identifier  MGI:4353890 Allele Type  Targeted
Gene  Pou4f2 Transmission  Germline
Strain of Origin  (129S6/SvEvTac x C57BL/6NCrl)F1 Is Recombinase  false
Is Wild Type  false
molecularNote  Sequence encoding three copies of the hemagglutinin (HA) epitope YPYDVPDYA were fused in frame 3' to the last exon of the gene locus. A floxed neomycin cassette was inserted downstream and was later removed by breeding founders with a cre deleter strain. Mice homozygous for this C-terminal "tagged" allele recapitulated wild-type expression patterns of the endogenous protein. Protein function was unaltered as determined by phenotypic analysis.
  • mutations:
  • Insertion
  • synonyms:
  • Pou4f2<HA>,
  • Pou4f2<HA>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories

Trail: Allele