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Protein Coding Gene : Fis1 fission, mitochondrial 1

Primary Identifier  MGI:1913687 Organism  mouse, laboratory
Chromosome  5 NCBI Gene Number  66437
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable identical protein binding activity; lipid binding activity; and molecular adaptor activity. Involved in mitochondrial fission. Located in mitochondrion. Is expressed in heart. Orthologous to human FIS1 (fission, mitochondrial 1).
PHENOTYPE: Mice homozygous for a conditional allele activated in skeletal muscle exhibit impaired exercise endurance with abnormal mitochondria. Mice homozygous for another conditional allele activated in male germ cells exhibit abnormal mitochondrial morphology and arrested spermatid maturation. [provided by MGI curators]
  • synonyms:
  • Ttc11,
  • Fis1,
  • RIKEN cDNA 2010003O14 gene,
  • tetratricopeptide repeat domain 11,
  • 2010003O14Rik,
  • fission, mitochondrial 1

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

0 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

2 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For