| Primary Identifier | MGI:2443149 | Organism | mouse, laboratory |
| Chromosome | 12 | NCBI Gene Number | 209334 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Predicted to enable several functions, including DNA endonuclease activity; magnesium ion binding activity; and protein homodimerization activity. Predicted to be involved in DNA metabolic process and regulation of cell cycle process. Predicted to act upstream of or within DNA repair. Predicted to be located in centrosome. Is expressed in embryo; metanephros; nephric duct; and neural tube. Orthologous to human GEN1 (GEN1 Holliday junction 5' flap endonuclease). PHENOTYPE: Mice homozygous for a hypomorphic allele exhibit abnormal kidney and urinary tract development. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
