Primary Identifier | MGI:3838227 | Allele Type | Spontaneous |
Attribute String | Hypomorph | Gene | Hcn2 |
Inheritance Mode | Recessive | Strain of Origin | DW/Pas |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Four base pairs (TTCA) were duplicated at nucleotide position 1669 in the cyclic nucleotide binding domain. RT-PCR confirmed a 90% decrease in transcript expression. The absence of protein expression was confirmed by immunohistochemistry on brain sections. |