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Allele : Braf<tm1Wds> Braf transforming gene; targeted mutation 1, William D Snider

Primary Identifier  MGI:3711006 Allele Type  Targeted
Attribute String  Conditional ready, No functional change Gene  Braf
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
description  Phenotypic Similarity to Human Syndrome: Neurocardiofaciocutaneous syndromes ( J:144862)
molecularNote  LoxP sites were inserted to flank exon 3 according to nomenclature in J:29234. An FRT-flanked neomycin resistance cassette was removed prior to ES cell injection. Deletion of exon 3 would cause a reading frame shift and introduce a translational stop codon at position 132, truncating the RBD, CRD and kinase domains.
  • mutations:
  • Insertion
  • synonyms:
  • Braf<f>,
  • Braf<f>,
  • Braf<exon3f>,
  • Braf<exon3f>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

7 Publication categories

Trail: Allele