Primary Identifier | MGI:5433216 | Allele Type | Transgenic |
Attribute String | Recombinase | Gene | Tg(Crx-cre)352Gla |
Strain of Origin | (C57BL/6J x SJL/J)F2 or (B6;129-Gt(ROSA)26Sor<tm1Sho>/J x (C57BL/6 x SJL)F1) | Is Recombinase | true |
Is Wild Type | false |
molecularNote | A construct with a 2.4 kb fragment of the Crx gene containing the promoter and proximal regulatory region driving cre cDNA followed by an SV40 polyadenylation sequence. The construct was generated from a plasmid that contained the Crx-Atoh7-IRES-cre sequence by excising the Atoh7 and IRES pieces. The purified Crx-cre transgene was injected into oocytes. 2 founders and 2 lines were obtained, crossed to GFP reporter mice, and analyzed for GFP and cre production. A representative line, 352, was analyzed in detail. |