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Protein Coding Gene : Ptger1 prostaglandin E receptor 1 (subtype EP1)

Primary Identifier  MGI:97793 Organism  mouse, laboratory
Chromosome  8 NCBI Gene Number  19216
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables D1 dopamine receptor binding activity. Involved in adenylate cyclase-activating dopamine receptor signaling pathway. Acts upstream of or within response to lipopolysaccharide. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in several structures, including alimentary system; brain; genitourinary system; immune system; and integumental system. Orthologous to human PTGER1 (prostaglandin E receptor 1).
PHENOTYPE: Homozygous null mice may exhibit partial prenatal lethality, pain threshold abnormalities, behavioral disinhibition in response to stress, low blood pressure, defects in type IV hypersensitivity reactions, resistance to chemically induced tumors and impaired response to water deprivation. [provided by MGI curators]
  • synonyms:
  • MGD-MRK-13660,
  • prostaglandin E receptor 1 (subtype EP1),
  • Ptgerep1,
  • EP1,
  • 42kDa,
  • prostaglandin E receptor EP1 subtype,
  • Ptger1

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

2 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

8 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For