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Allele : Drd2<tm1Schm> dopamine receptor D2; targeted mutation 1, Claudia Schmauss

Primary Identifier  MGI:2388386 Allele Type  Targeted
Attribute String  Null/knockout Gene  Drd2
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  A 3' portion of exon 2 was replaced with a neomycin selection cassette inserted by homologous recombination. The deleted region encoded the amino terminal extracellular domain, transmembrane spanning domains 1 and 2, and the first intracellular domain. Transcript was undetected by Northern blot analysis of RNA obtained from the dorsal striatum of homozygous mutant mice.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • D2 -,
  • D2R-KO,
  • D2R-KO,
  • D2 -
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

Trail: Allele

0 Driven By

17 Publication categories

Trail: Allele