Primary Identifier | MGI:2158716 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Chrnb4 |
Transmission | Germline | Strain of Origin | 129S7/SvEvBrd-Hprt1<b-m2> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A 4.1 kb genomic fragment containing exon 5 was replaced with a puromycin selection gene and an hprt minigene. RT-PCR analysis on RNA derived from brain of homozygous mice demonstrated that no detectable transcript is produced from this allele. |