| Primary Identifier | MGI:5763098 | Allele Type | Endonuclease-mediated |
| Gene | Psmb11 | Strain of Origin | Not Specified |
| Is Recombinase | false | Is Wild Type | false |
| description | Guide RNA and hCas9 mRNA were injected into fertilized eggs from either (C57BL/6 x DBA/2)F1 x C57BL/6-Psmb11Tn or C57BL/6 x C57BL/6-Psmb11Tn. |
| molecularNote | CRISPR technology was used to generate a G to A nucleotide substitution that results in the amino acid substitution of arginine for glycine at position 220 (G220R). Founder 2 is heterozygous for the expected point mutation wthout any additional mutations. Founder 28 is heterozygous for the expected point mutation without any additional mutations. |
