Primary Identifier | IPR035394 | Type | Domain |
Short Name | Glyco_hydro_59_dom |
description | This entry represents the central domain of the glycosyl hydrolase family 59 members.Glycoside hydrolase family 59 comprises enzymes with only one known activity; galactocerebrosidase ().Globoid cell leukodystrophy (Krabbe disease) is a severe, autosomalrecessive disorder that results from deficiency of galactocerebrosidase(GALC) activity [, , ]. GALC is responsible for the lysosomal catabolism ofcertain galactolipids, including galactosylceramide and psychosine []. |