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Allele : Itm2c<em2(IMPC)Tcp> integral membrane protein 2C; endonuclease-mediated mutation 2, The Centre for Phenogenomics

Primary Identifier  MGI:6257738 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Itm2c
Inheritance Mode  Not Specified Strain of Origin  C57BL/6NCrl
Is Recombinase  false Is Wild Type  false
Project Collection  IMPC
molecularNote  This allele produced from project TCPR0313 at TCP by injecting Cas9 mRNA and one guide RNA with the spacer sequence CCTTTCCGGGAGCGGTGGCG. This resulted in a 15-bp deletion from Chr1:85903021 to 85903035_insT (GRCm38) in ENSMUSE00000330277. This mutation is predicted to cause a frameshift with amino acid changes after residue 48 and early truncation 40 amino acids later (p.R48Efs*42). (GRCm38).
  • mutations:
  • Insertion,
  • Intragenic deletion
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

Trail: Allele

0 Driven By

4 Publication categories

Trail: Allele