| First Author | Coste SC | Year | 2001 |
| Journal | Peptides | Volume | 22 |
| Issue | 5 | Pages | 733-41 |
| PubMed ID | 11337086 | Mgi Jnum | J:88769 |
| Mgi Id | MGI:3037067 | Doi | 10.1016/s0196-9781(01)00386-2 |
| Citation | Coste SC, et al. (2001) Animal models of CRH excess and CRH receptor deficiency display altered adaptations to stress. Peptides 22(5):733-41 |
| abstractText | This review highlights new information gained from studies using recently developed animal models that harbor specific alterations in corticotropin-releasing hormone (CRH) pathways. We discuss features of a transgenic mouse model of chronic CRH overexpression and two mouse models that lack either CRH receptor type 1 (CRH-R1) or type 2 (CRH-R2). Together these models provide new insights into the role of CRH pathways in promoting stability through adaptive changes, a process known as allostasis. |
