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Protein Coding Gene : Slc22a8 solute carrier family 22 (organic anion transporter), member 8
Primary Identifier  MGI:1336187 Organism  mouse, laboratory
Chromosome  19 NCBI Gene Number  19879
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables antiporter activity and organic anion transmembrane transporter activity. Predicted to be involved in glutathione transport; prostaglandin transport; and quaternary ammonium group transport. Predicted to act upstream of or within lipid transport; monoatomic ion transport; and response to toxic substance. Predicted to be located in apical plasma membrane and basolateral plasma membrane. Is expressed in several structures, including central nervous system; genitourinary system; liver; spleen; and thyroid gland. Orthologous to human SLC22A8 (solute carrier family 22 member 8).
PHENOTYPE: Mice homozygous for a null allele exhibit decreased urinary urate levels. [provided by MGI curators]
  • synonyms:
  • OAT3,
  • reduced in osteosclerosis transporter,
  • mOat3,
  • Slc22a8,
  • Roct,
  • solute carrier family 22 (organic anion transporter), member 8
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Trail: ProteinCodingGene

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