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Protein Domain : BRI3-binding protein

Primary Identifier  IPR033367 Type  Family
Short Name  BRI3BP
description  BRI3-binding protein (BRI3BP) is a mitochondria protein and a binding partner for HCCR-1, which is overexpressed in various human tumours and appears to serve as a negative regulator of the p53 gene []. BRI3BP may also be involved in the structural dynamics of the ER and affects mitochondrial viability. It possesses a pro-apoptotic property and can potentiate drug-induced apoptosis [].

0 Child Features

0 Parent Features

2 Protein Domain Regions