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Allele : Tg(Rr280-EGFP)nPE2Mrub transgene insertion nPE2, Marcelo Rubinstein
Primary Identifier  MGI:7343821 Allele Type  Transgenic
Attribute String  Reporter Gene  Tg(Rr280-EGFP)nPE2Mrub
Is Recombinase  false Is Wild Type  false
molecularNote  The transgene contains the following elements: a neuron-specific enhancers-containing region 9-13 kb upstream of the Pomc gene transcription start site with enhancer Rr279 deleted but Rr280 still present, and the Pomc gene, including 0.8 kb of upstream and 8 kb of downstream sequence, with the EGFP reporter gene and SV40 poly(A) signal sequences inserted upstream of the translation start site. The deleted region 0.8-9 kb upstream of Pomc contains pituitary enhancer Rr181. The transgene is expressed in hypothalamic arcuate neurons during embryonic development.
  • mutations:
  • Insertion
  • synonyms:
  • nPE2-EGFP,
  • nPE2-EGFP
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele




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