| Primary Identifier | MGI:1930964 | Organism | mouse, laboratory |
| Chromosome | 8 | NCBI Gene Number | 59016 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Enables DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Acts upstream of or within several processes, including electron transport chain; negative regulation of neuron apoptotic process; and regulation of DNA-templated transcription. Predicted to be located in cytosol. Predicted to be part of RNA polymerase II transcription regulator complex. Predicted to be active in nucleoplasm. Is expressed in 1-cell stage embryo; brain ventricular layer; forelimb bud; inferior colliculus; and oocyte. Used to study methylmalonic aciduria and homocystinuria type cblC. Orthologous to human THAP11 (THAP domain containing 11). PHENOTYPE: Homozygous inactivation of this gene leads to peri-implantation lethality and defects in the inner cell mass. Homozygous null ES cells are not viable. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
