| Primary Identifier | MGI:892968 | Organism | mouse, laboratory |
| Chromosome | 3 | NCBI Gene Number | 21338 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable tachykinin receptor activity. Predicted to be involved in several processes, including positive regulation of flagellated sperm motility; positive regulation of uterine smooth muscle contraction; and response to estradiol. Predicted to act upstream of or within G protein-coupled receptor signaling pathway. Predicted to be located in dendrite membrane and neuronal cell body membrane. Predicted to be active in plasma membrane and sperm midpiece. Is expressed in several structures, including alimentary system; genitourinary system; integumental system; nervous system; and sensory organ. Used to study hypogonadotropic hypogonadism 11 with or without anosmia. Human ortholog(s) of this gene implicated in hypogonadotropic hypogonadism 11 with or without anosmia. Orthologous to human TACR3 (tachykinin receptor 3). PHENOTYPE: Mice homozygous for a knock-out allele exhibit increased body weight, cognitive deficits in tests associated with learning and memory and symptoms of hypogonadotropic hypogonadism. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
