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Protein Coding Gene : Serpinb5 serine (or cysteine) peptidase inhibitor, clade B, member 5

Primary Identifier  MGI:109579 Organism  mouse, laboratory
Chromosome  1 NCBI Gene Number  20724
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable serine-type endopeptidase inhibitor activity. Acts upstream of or within several processes, including extracellular matrix organization; prostate gland morphogenesis; and regulation of epithelial cell proliferation. Located in sarcoplasm. Is active in cornified envelope. Is expressed in several structures, including alimentary system; genitourinary system; integumental system; respiratory system; and sensory organ. Orthologous to human SERPINB5 (serpin family B member 5).
PHENOTYPE: Mice homozygous for one null allele displayed peri-implantation lethality with impaired endoderm development and attenuated inner cell mass growth. Mice homozygous for another null allele were viable and fertile with no gross abnormalities. [provided by MGI curators]
  • synonyms:
  • RIKEN cDNA 1110036M19 gene,
  • MGI:2138309,
  • AI462524,
  • AI646751,
  • Spi7,
  • ovalbumin,
  • MGI:2138262,
  • MGD-MRK-39578,
  • expressed sequence AI646751,
  • serine (or cysteine) peptidase inhibitor, clade B, member 5,
  • Maspin,
  • 1110036M19Rik,
  • MGI:1915965,
  • serine protease inhibitor 7,
  • Serpinb5,
  • expressed sequence AI462524

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3 Involved In Mutations

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Canonical gene --> Transcripts in specific strains.

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