| Primary Identifier | MGI:2138446 | Organism | mouse, laboratory |
| Chromosome | 1 | NCBI Gene Number | 245860 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable phospholipid scramblase activity. Involved in autophagy; bone morphogenesis; and programmed necrotic cell death. Acts upstream of or within several processes, including autophagosome assembly; negative regulation of cytokine production; and protein localization to Golgi apparatus. Located in Golgi membrane; autophagosome; and endoplasmic reticulum membrane. Is active in synaptic membrane. Is expressed in brain; cochlea; heart; liver; and lung. Orthologous to human ATG9A (autophagy related 9A). PHENOTYPE: Mice homozygous for a null mutation all die within 1 day of birth and display impaired autophagy. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
