Primary Identifier | MGI:1915266 | Organism | mouse, laboratory |
Chromosome | 4 | NCBI Gene Number | 68016 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable GTPase activator activity. Acts upstream of or within positive regulation of transcription by RNA polymerase II. Located in Z disc; caveola; and sarcoplasm. Is expressed in cardiovascular system; lung; and skeletal muscle. Orthologous to human CAVIN4 (caveolae associated protein 4). PHENOTYPE: Homozygous null mice are viable and fertile with normal cardiac mass and function under physiological conditions. Phenylephrine-induced cardiac hypertrophy is suppressed in null mice. [provided by MGI curators] |