| Primary Identifier | MGI:2653863 | Organism | mouse, laboratory |
| Chromosome | 1 | NCBI Gene Number | 227289 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable G protein-coupled bile acid receptor activity. Involved in regulation of bicellular tight junction assembly. Predicted to be located in cytoplasm. Predicted to be part of receptor complex. Predicted to be active in plasma membrane. Is expressed in gut and male reproductive gland or organ. Orthologous to human GPBAR1 (G protein-coupled bile acid receptor 1). PHENOTYPE: Mutations in this gene result in abnormal cholesterol, bile, and insulin homeostasis. Mice homozygous for a conditional allele activated in adipose tissue are resistant to the improvements in adipose tissue thermogenesis that occur in the diet-induced obesity model of intestine-specific Hif1a knockout. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
