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Protein Coding Gene : Rictor RPTOR independent companion of MTOR, complex 2

Primary Identifier  MGI:1926007 Organism  mouse, laboratory
Chromosome  15 NCBI Gene Number  78757
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.3.0)

Enables ribosome binding activity. Involved in embryo development; regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction; and regulation of protein phosphorylation. Acts upstream of or within several processes, including positive regulation of actin filament polymerization; regulation of establishment of cell polarity; and regulation of protein phosphorylation. Part of TORC2 complex. Is expressed in early conceptus and oocyte. Human ortholog(s) of this gene implicated in breast ductal carcinoma; gastrointestinal system cancer (multiple); and lung cancer (multiple). Orthologous to human RICTOR (RPTOR independent companion of MTOR complex 2).
PHENOTYPE: Mice homozygous for a null allele exhibit embryonic lethality during organogenesis associated with abnormal placental morphology. [provided by MGI curators]
  • synonyms:
  • MGI:1925833,
  • MGI:2146218,
  • expressed sequence AW492497,
  • AW492497,
  • MGI:1924409,
  • RIKEN cDNA 4921505C17 gene,
  • Rictor,
  • RIKEN cDNA D530039E11 gene,
  • 6030405M08Rik,
  • RIKEN cDNA 6030405M08 gene,
  • 4921505C17Rik,
  • RPTOR independent companion of MTOR, complex 2,
  • D530039E11Rik

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Genome

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0 CDSs

0 Exons

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1 Involved In Mutations

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0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

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Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

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Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

23 Pathways

0 Targeted By

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Expression

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Disease

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