| First Author | DiLella AG | Year | 1991 |
| Journal | Biochem Biophys Res Commun | Volume | 179 |
| Issue | 3 | Pages | 1427-33 |
| PubMed ID | 1930186 | Mgi Jnum | J:11520 |
| Mgi Id | MGI:59947 | Doi | 10.1016/0006-291x(91)91732-r |
| Citation | DiLella AG (1991) Chromosomal assignment of the human immunophilin FKBP-12 gene. Biochem Biophys Res Commun 179(3):1427-33 |
| abstractText | FKBP-12 is the major T cell binding protein for the immunosuppressive drugs FK506 and rapamycin. It is a member of the immunophilin family of proteins which are believed to play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. The chromosomal assignment of the human FKBP-12 gene was determined by using the polymerase chain reaction to amplify an intron-containing region of the gene in purified DNA isolated from 42 human-rodent somatic cell hybrids. The results of this analysis indicated that the FKBP-12 gene resides on human chromosome 20. |
