Primary Identifier | IPR029921 | Type | Family |
Short Name | NEB2 |
description | Neurabin-2 (NEB2 also known as spinophilin) is a multi-domain multifunctional scaffold protein that takes part in several protein interactions. It binds to many proteins with different functions, including protein phosphatase 1 and F-actin []. Neurabin-2/spinophilin probably regulates both membrane and cytoskeletal functions []. It plays important functions in the nervous system where it modulates excitatory synaptic transmission and dendritic spine morphology []. It may be a tumour suppressor []. |