| Primary Identifier | MGI:2140327 | Organism | mouse, laboratory |
| Chromosome | 4 | NCBI Gene Number | 100169 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Enables actin binding activity; protein phosphatase 1 binding activity; and protein phosphatase activator activity. Involved in several processes, including enteric nervous system development; morphogenesis of embryonic epithelium; and negative regulation of integrin-mediated signaling pathway. Located in lamellipodium. Is expressed in several structures, including 1st branchial arch mandibular component; central nervous system; facial prominence; and retina. Orthologous to human PHACTR4 (phosphatase and actin regulator 4). PHENOTYPE: Mice homozygous for a null allele exhibit embryonic and neonatal lethality, exencephaly, neural tube defects, coloboma, and altered cell cycles. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
