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Protein Coding Gene : Mst1 macrophage stimulating 1 (hepatocyte growth factor-like)

Primary Identifier  MGI:96080 Organism  mouse, laboratory
Chromosome  9 NCBI Gene Number  15235
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable histone kinase activity and receptor tyrosine kinase binding activity. Acts upstream of or within several processes, including embryo implantation; mammary duct terminal end bud growth; and positive regulation of mammary gland epithelial cell proliferation. Located in vacuole. Is expressed in esophagus epithelium; liver; liver parenchyma; pharynx epithelium; and stomach proventricular region epithelium. Orthologous to several human genes including MST1 (macrophage stimulating 1).
PHENOTYPE: Mice homozygous for a knock-out allele exhibit lipid-filled cytoplasmic vacuoles in hepatocytes throughout the liver lobules. [provided by MGI curators]
  • synonyms:
  • MGD-MRK-8535,
  • hepatocyte growth factor-like,
  • Hgfl,
  • MGD-MRK-6224,
  • MGD-MRK-10705,
  • D9H3F15S2,
  • DNF15S2h,
  • DNA segment, Chr 9, human D3F15S2,
  • macrophage stimulating 1 (hepatocyte growth factor-like),
  • D3F15S2h,
  • Mst1,
  • MGD-MRK-8876

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Genome

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Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

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Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

3 Pathways

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Disease

Mouse features --> Human diseases

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