|  Help  |  About  |  Contact Us

Protein Coding Gene : St8sia4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4

Primary Identifier  MGI:106018 Organism  mouse, laboratory
Chromosome  1 NCBI Gene Number  20452
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity. Involved in sialylation. Predicted to be located in Golgi apparatus. Is expressed in several structures, including central nervous system; genitourinary system; gut; hemolymphoid system gland; and lung. Orthologous to human ST8SIA4 (ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4).
PHENOTYPE: Homozygous null adult mice exhibit impaired long term potentiation and impaired long term depression in hippocampal CA1 synapses. [provided by MGI curators]
  • synonyms:
  • Siat8d,
  • MGD-MRK-33700,
  • ST8SiaIV,
  • PST,
  • St8sia4,
  • PST-1,
  • ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4,
  • sialyltransferase 8 (alpha-2, 8-sialyltransferase) D

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

2 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

11 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For