| Primary Identifier | MGI:1353452 | Organism | mouse, laboratory |
| Chromosome | 11 | NCBI Gene Number | 11671 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Enables aldehyde dehydrogenase (NAD+) activity. Predicted to be involved in several processes, including hexadecanal metabolic process; nervous system development; and terpenoid metabolic process. Predicted to act upstream of or within fatty acid metabolic process. Located in endoplasmic reticulum and membrane. Is expressed in several structures, including alimentary system; decidua; early conceptus; nervous system; and sensory organ. Human ortholog(s) of this gene implicated in Sjogren-Larsson syndrome. Orthologous to human ALDH3A2 (aldehyde dehydrogenase 3 family member A2). PHENOTYPE: Homozygous null mice exhibit impaired long-chain base metabolism, hyperproliferation of keratinocytes, widened intercellular spaces in the basal layer of the epidermis, and delayed barrier recovery after stratum corneum perturbation. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
