| Primary Identifier | MGI:1929278 | Organism | mouse, laboratory |
| Chromosome | 4 | NCBI Gene Number | 56374 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Enables endopeptidase activity. Predicted to be involved in negative regulation of protein localization to plasma membrane and positive regulation of autophagy. Predicted to act upstream of or within with a negative effect on protein glycosylation. Predicted to act upstream of or within autophagy. Predicted to be located in Golgi cis cisterna; Golgi medial cisterna; and Golgi trans cisterna. Predicted to be active in late endosome and lysosome. Is expressed in several structures, including alveolar sulcus; central nervous system; olfactory epithelium; retina; and skeleton. Orthologous to human TMEM59 (transmembrane protein 59). PHENOTYPE: Mice homozygous for a null allele display reduced dendritic arborization, reduced miniature excitatory postsynaptic currents, and impaired memory formation. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
