Primary Identifier | IPR045827 | Type | Domain |
Short Name | VCPIP1_N |
description | Deubiquitinating protein VCPIP1, also known as VCIP135, is required for the p97/p47 and p97/p37 pathways and is involved in Golgi and ER membrane fusion. It reverses ubiquitination events that occurs during mitotic disassembly, regulating Golgi membrane dynamics during mitosis. This entry represents the N-terminal domain that interacts with WAC (the WW domain-containing adaptor with coiled coil). This interaction increases the deubiquitinating activity of VCPIP1 and is necessary for p97/p47-mediated Golgi membrane fusion [, ]. |