| Primary Identifier | MGI:5779204 | Allele Type | Targeted |
| Attribute String | Not Specified | Gene | Grin2a |
| Transmission | Germline | Strain of Origin | (C57BL/6NCrlj x CBA/JNCrlj)F1 |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | The targeting vector inserted uptream of the endogenous exon 10 a floxed neomycin resistance cassette. The targeting vector also inserted downstream of the endogenous exon 10 a loxP site, 48 nucleotide spacer sequence and a modified exon 10 with nucleotide substitutions (AAC to CAG). The substitutions results in the amino acid substitution of glutamine for asparagine at position 595 (N595Q). Cre-mediated recombination removed the selection cassette and left the endogenous exon 10 floxed. |
