| Primary Identifier | MGI:95617 | Organism | mouse, laboratory |
| Chromosome | 7 | NCBI Gene Number | 110886 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable GABA receptor binding activity and ligand-gated monoatomic ion channel activity. Predicted to contribute to GABA-A receptor activity; benzodiazepine receptor activity; and chloride channel activity. Involved in cochlea development; inner ear receptor cell development; and innervation. Acts upstream of or within associative learning and behavioral fear response. Located in cell body and dendrite. Is expressed in brain and palatal shelf. Human ortholog(s) of this gene implicated in bipolar disorder; depressive disorder; and developmental and epileptic encephalopathy 79. Orthologous to human GABRA5 (gamma-aminobutyric acid type A receptor subunit alpha5). PHENOTYPE: Mice having disruptions in this gene display abnormalities in hearing and in ear structure. Subtle abnormalities in learning and in conditioning have also been reported. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
