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Protein Coding Gene : Atp1a4 ATPase, Na+/K+ transporting, alpha 4 polypeptide

Primary Identifier  MGI:1351335 Organism  mouse, laboratory
Chromosome  1 NCBI Gene Number  27222
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Enables P-type sodium:potassium-exchanging transporter activity. Acts upstream of or within several processes, including flagellated sperm motility; sodium ion transport; and spermatogenesis. Predicted to be located in rod photoreceptor outer segment and sperm midpiece. Predicted to be part of sodium:potassium-exchanging ATPase complex. Predicted to be active in cell projection and plasma membrane. Is expressed in choroid plexus; epididymis; and testis. Orthologous to human ATP1A4 (ATPase Na+/K+ transporting subunit alpha 4).
PHENOTYPE: Male mice homozygous for a knock-out allele exhibit infertility associated with asthenozoospermia and teratozoospermia. [provided by MGI curators]
  • synonyms:
  • ATPase, Na+/K+ transporting, alpha 4 polypeptide,
  • Atp1a4

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

2 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

6 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For