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Protein Coding Gene : Trat1 T cell receptor associated transmembrane adaptor 1

Primary Identifier  MGI:1924897 Organism  mouse, laboratory
Chromosome  16 NCBI Gene Number  77647
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to be involved in negative regulation of receptor recycling and positive regulation of T cell receptor signaling pathway. Predicted to act upstream of or within negative regulation of transport and positive regulation of calcium-mediated signaling. Predicted to be located in centriolar satellite; mitotic spindle; and plasma membrane. Predicted to be part of T cell receptor complex. Orthologous to human TRAT1 (T cell receptor associated transmembrane adaptor 1).
PHENOTYPE: Mice with homozygous disruption of this gene display decreased body weight and a proportional reduction in lymph organ cell numbers; however T and B cell function are normal. [provided by MGI curators]
  • synonyms:
  • RIKEN cDNA C030046M14 gene,
  • Trat1,
  • T cell receptor associated transmembrane adaptor 1,
  • T-cell receptor interacting molecule,
  • Tcrim,
  • C030046M14Rik,
  • Trim

Features --> Cross References

Genome

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

0 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

9 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

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0 Driver For